Hornberg, Jorrit J: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Exploratory toxicology as an integrated part of drug discovery. Part II: Screening strategies

Hornberg, Jorrit J., Laursen, Morten, Brenden, Nina, Persson, Mikael, Thougaard, Annemette V., Toft, Dorthe B., Mow, Tomas

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 876 KB

english, 2014

2

Exploratory toxicology as an integrated part of drug discovery. Part I: Why and how

Hornberg, Jorrit J., Laursen, Morten, Brenden, Nina, Persson, Mikael, Thougaard, Annemette V., Toft, Dorthe B., Mow, Tomas

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 966 KB

english, 2014

3

Predictive in vitro toxicology screening to guide chemical design in drug discovery

Johansson, Julia, Larsson, Marie H., Hornberg, Jorrit J.

Journal:

Current Opinion in Toxicology

Year:

2019

Language:

english

File:

PDF, 2.11 MB

english, 2019

4

Cancer: A Systems Biology disease

Jorrit J. Hornberg, Frank J. Bruggeman, Hans V. Westerhoff, Jan Lankelma

Journal:

Year:

2006

Language:

english

File:

PDF, 308 KB

english, 2006

5

Synergistic activation of signalling to extracellular signal-regulated kinases 1 and 2 by epidermal growth factor and 4β-phorbol 12-myristate 13-acetate

Jorrit J. Hornberg, Marloes R. Tijssen, Jan Lankelma

Journal:

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

6

Principles behind the multifarious control of signal transduction : ERK phosphorylation and kinase/phosphatase control

Jorrit J. Hornberg, Frank J. Bruggeman, Bernd Binder, Christian R. Geest, A. J. Marjolein Bij de Vaate, Jan Lankelma, Reinhart Heinrich, Hans V. Westerhoff

Journal:

Year:

2005

Language:

english

File:

PDF, 348 KB

english, 2005

7

Control of MAPK signalling: from complexity to what really matters

Hornberg, Jorrit J, Binder, Bernd, Bruggeman, Frank J, Schoeberl, Birgit, Heinrich, Reinhart, Westerhoff, Hans V

Journal:

Year:

2005

Language:

english

File:

PDF, 276 KB

english, 2005

8

Oncogenes are to lose control on signaling following mutation

Jorrit J. Hornberg, Hans V. Westerhoff

Journal:

Molecular Biotechnology

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

9

Epidermal growth factor receptor-induced activator protein 1 activity controls density-dependent growth inhibition in normal rat kidney fibroblasts

Jorrit J. Hornberg, Henk Dekker, Peter H. J. Peters, Petra Langerak, Hans V. Westerhoff, Jan Lankelma, Everardus J. J. van Zoelen

Journal:

Molecular Biotechnology

Year:

2006

Language:

english

File:

PDF, 815 KB

english, 2006

10

A potential imprint control element: identification of a conserved 42 bp sequence upstream of H19

Mathias A.E. Frevel, Jorrit J. Hornberg, Anthony E. Reeve

Journal:

Trends in Genetics

Year:

1999

Language:

english

File:

PDF, 140 KB

english, 1999

11

Finding the way in the jungle of kinase drug targets

Ellinor Oxelmark, Jorrit J. Hornberg

Journal:

Drug Discovery Today: Technologies

Year:

2007

Language:

english

File:

PDF, 128 KB

english, 2007

12

High-Content Analysis/Screening for Predictive Toxicology: Application to Hepatotoxicity and Genotoxicity

Persson, Mikael, Løye, Anni F., Jacquet, Mélanie, Mow, Natacha S., Thougaard, Annemette V., Mow, Tomas, Hornberg, Jorrit J.

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2014

Language:

english

File:

PDF, 328 KB

english, 2014

13

A high content screening assay to predict human drug-induced liver injury during drug discovery

Persson, Mikael, Løye, Anni F., Mow, Tomas, Hornberg, Jorrit J.

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2013

Language:

english

File:

PDF, 1.64 MB

english, 2013

14

Editorial Board

Hornberg, Jorrit J., Laursen, Morten, Brenden, Nina, Persson, Mikael, Thougaard, Annemette V., Toft, Dorthe B., Mow, Tomas

Journal:

Year:

1983

File:

PDF, 25 KB

1983

15

How can we discover safer drugs?

Hornberg, Jorrit J, Mow, Tomas

Journal:

Future Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 870 KB

english, 2014

16

Validation of a high throughput flow cytometric in vitro micronucleus assay including assessment of metabolic activation in TK6 cells

Thougaard, Annemette V., Christiansen, Joan, Mow, Tomas, Hornberg, Jorrit J.

Journal:

Environmental and Molecular Mutagenesis

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

17

Advances in Predictive Toxicology for Discovery Safety through High Content Screening

Persson, Mikael, Hornberg, Jorrit J.

Journal:

Chemical Research in Toxicology

Year:

2016

Language:

english

File:

PDF, 4.38 MB

english, 2016

18

Development of a high content assay in ciPTEC-OAT1 as an in vitro model to predict drug-induced nephrotoxicity

Sjogren, Anna-Karin, Breitholtz, Katarina, Forsgard, Malin, Milton, Lucas, Stahl, Simone, Fenner, Katherine, Wilmer, Martijn, Persson, Mikael, Hornberg, Jorrit

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 55 KB

english, 2017

19

Use of ex-vivo testis culture to explore mechanisms of seminiferous tubular atrophy upon PIM inhibition

Larsson, Marie H., Andersson, Ulf, Harris, Jayne, Hornberg, Jorrit J., Mitchard, Terri

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 54 KB

english, 2017

20

A novel multi-parametric high content screening assay in ciPTEC-OAT1 to predict drug-induced nephrotoxicity during drug discovery

Sjögren, Anna-Karin, Breitholtz, Katarina, Ahlberg, Ernst, Milton, Lucas, Forsgard, Malin, Persson, Mikael, Stahl, Simone H., Wilmer, Martijn J., Hornberg, Jorrit J.

Journal:

Archives of Toxicology

Year:

2018

Language:

english

File:

PDF, 1.39 MB

english, 2018

21

Compound selection and annotation to validate the predictivity of in vitro toxicity assays for use in drug discovery, in response to Commentary by Dr. Zink (Zink, D. Arch Toxicol (2018))

Sjögren, Anna-Karin, Hornberg, Jorrit J.

Journal:

Archives of Toxicology

Year:

2018

Language:

english

File:

PDF, 553 KB

english, 2018

22

Analysis of Multiple Gene Expression Array Experiments after Repetitive Hybridizations on Nylon Membranes

Hornberg, Jorrit J., Haas, Richard R. de, Dekker, Henk, Lankelma, Jan

Journal:

Year:

2002

File:

PDF, 106 KB

2002

23

In vitro prediction of organ toxicity: the challenges of scaling and secondary mechanisms of toxicity

Hengstler, Jan G., SjÃ¶gren, Anna-Karin, Zink, Daniele, Hornberg, Jorrit J.

Journal:

Archives of Toxicology

Year:

2020

Language:

english

File:

PDF, 727 KB

english, 2020